IFPA Trainer Practice Exam

What production can lead to a dangerous metabolic situation?

1. Rigor mortis

2. Krebs cycle

3. Ketone bodies

4. Muscular activity

The correct answer is: Ketone bodies

The production of ketone bodies can lead to a dangerous metabolic situation, specifically when there is excessive accumulation in the body, a condition known as ketosis. Ketone bodies are produced by the liver during periods of low carbohydrate intake, prolonged fasting, or uncontrolled diabetes. When the body does not have enough glucose for energy, it breaks down fat stores, leading to the generation of ketone bodies as an alternative energy source. In a healthy scenario, ketone bodies can provide energy and serve as a metabolic pathway. However, when their production becomes excessive, it can result in ketoacidosis, particularly in individuals with diabetes. This condition is characterized by high levels of ketones in the blood, lowering the pH and leading to acidosis, which can become life-threatening if not treated promptly. In contrast, rigor mortis refers to the stiffening of muscles after death due to biochemical changes; it doesn't cause metabolic distress while alive. The Krebs cycle is a crucial metabolic pathway that generates energy but does not inherently lead to dangerous situations when functioning normally. Muscular activity involves energy expenditure and could lead to fatigue or temporary lactic acidosis, but it is not pathologically dangerous in the same manner as an excessive accumulation of ketone bodies.